PrimeStore® Molecular Transport Medium (MTM) was designed to rapidly inactivate viruses (including Influenza), bacteria (including MTB) and high consequence veterinary pathogens (including ASFv, CSFv, FMDv, HPAI, and NDv) within the sample and stabilize the RNA and DNA to provide safer and more efficient workflow for molecular testing and sequencing. The cold chain is not needed for transportation from collection to the laboratory. It disrupts/lyses lipid membranes, destroys proteins and enzymes, inactivates nucleases and proteases, inactivates infectious biological pathogens, including gram-positive/negative bacteria and viruses, and preserves/stabilizes ‘naked’ RNA/DNA at elevated temperatures.
PrimeStore® MTM is compatible with most silica based spin column and magnetic bead extraction kits and systems to include those from Thermo Fisher, Roche Molecular, Qiagen, and BioMerieux. The 2019 MagMax Ultra kit kit may not provide optimized yields out of PrimeStore® MTM.
LHNVD has other molecular grade transport products if viability of the sample is required.
*Tested by USDA Foreign Animal Disease Diagnostic Laboratory
PrimeStore MTM for Microbial Inactivation
PrimeStore® MTM is intended for the stabilization, transportation and inactivation of infectious unprocessed nasal washes suspected of containing Influenza A virus RNA. PrimeStore® MTM is also intended for the stabilization, transportation and inactivation of infectious unprocessed sputum samples suspected of containing Mycobacterium tuberculosis DNA from human samples.
PrimeStore® MTM has been demonstrated to completely inactivate viruses, bacteria, and fungi. Multiple studies have demonstrated that PrimeStore® MTM reduces Bacillus spores by three to four logs. Samples suspected of containing spores should be treated as though viable spores remain.
PrimeStore for the Developing World
Sample collection is one of the greatest challenges in the developing world. Whether in a remote village or a densely populated city, collecting a quality sample and transporting it in a safe a timely manner to a laboratory that can effectively test that sample using modern molecular platforms is a current challenge that is greatly alleviated by PrimeStore® MTM.
PrimeStore® MTM has been used by researchers in remote regions of Nepal, India, China, South Africa, Peru, Pakistan, Papua New Guinea, and Ukraine, as well as densely populated cities such as Mumbai, Pretoria, Macau and Singapore. Human, animal, and plant samples shipped in PrimeStore® MTM consistently outperform other sample collection systems leading to more effective and accurate molecular testing. Even where point of care systems such as the Cepheid GeneXpert MTB/RIF test are deployed, PrimeStore® MTM has demonstrated the ability to improve sensitivity in low copy samples and allow for the same sample to be transported for additional drug susceptibility testing (DST).
Most pandemic diseases originate from the developing world. The ability to screen samples for novel and emerging pathogens using the most modern and accurate molecular tests is essential for early detection and action to prevent large outbreaks.
Special pricing is available for the developing world.